A Case of Autoimmune Hepatitis with Microadenoma of Pituitary
Usha Singh1*, Varnika Rai1, Hema Goyal1, Rajeev Singh2, N K Agarwal3, Nehal Ahmad1, Deepa Santhosh1*
Affiliation
- 1Department of Pathology, IMS BHU, Varanasi, India
- 2Department of Radiodiagnosis and Imaging IMS BHU, Varanasi, India
- 3Department of Endocrinology, IMS BHU, Varanasi, India
Corresponding Author
Dr. Usha Singh, Professor and Head, Department of Pathology, UGC adv. IMS BHU, Varanasi, India; E-mail: vrachievers@gmail.com
Citation
Singh, U., et al. A Case of Autoimmune Hepatitis with Microadenoma of Pituitary. (2016) Intl J Cancer Oncol 3(1): 1-2.
Copy rights
© 2016 Singh, U. This is an Open access article distributed under the terms of Creative Commons Attribution 4.0 International License.
Keywords
Abstract
Here, a case of autoimmune hepatitis in 34 yrs old lady has been described. She presented with prolonged jaundice, amenorrhea, arthritis and lactation. In laboratory examination, her aminotransferases, alkaline phosphatase and all immunoglobulins were raised. Her serum was positive for antinuclear antibody, anti SLA antibody and antibody to F-actin. Other autoantibodies like anti ds DNA, anti SSA, anti SSB, anti Scl 70, anti Jo-1, anti-centromere and anti-cardiolipinAb were negative. There were no clinical features of any other autoimmune disease. On MRI examination, microadenoma of pituitary gland was detected and her serum prolactin & T4 level were also high. She was finally diagnosed as a case of AIH with pituitary microadenomaand anti SLA Ab, which is an uncommon entity.She was kept on steroid and Bromocriptine, but follow up could not be done. This case suggests that AutoImmune Hepatitis (AIH) with ANA, F-actin and anti SLAAb may present with Prolactinoma.
