Affiliation

• ¹KNOTUS Co., Ltd. Research Center, 189, Donggureung-Ro, Guri-Si, Gyeonggi-Do, Republic of Korea
• ²Infopia Co., Ltd. 132, Anyang, Cheondong-ro, Dongan-gu, Anyang-si, Gyeonggi-do, Republic of Korea

Corresponding Author

Do-Hyung Kim, Chief of laboratory, KNOTUS Co., Ltd. 189 Donggureung-Ro, Guri-Si, Gyeonggi-Do, Republic of Korea, Tel: +82-31-572-8899; Fax: +82-31-572-6699; E-mail: lab@knotus.co.kr

Citation

Rahman, M. M., et al. Accuracy and Clinical Utility of Selexon™ Canine D-Dimer Device in Measuring of Blood D-Dimer Level in Healthy and Diseased Dogs. (2017) J Vet Sci Animal Welf 2(1): 1- 4.

Copy rights

© 2017 Kim, D.H. This is an Open access article distributed under the terms of Creative Commons Attribution 4.0 International License.

Keywords

Abstract

  D-dimer is a protein fragment and degradation product of fibrin which is a sensitive tool for early diagnosis of thromboembolic disease such as pulmonary thromboembolism (PTE) and disseminated intravascular coagulation (DIC) both in human and veterinary practice. The objective of this study was to evaluate the accuracy and clinical utility of SelexOn™ canine D-dimer device (Infopia, Korea) in comparison to the NycoCard™ D-dimer (Nycomed Pharma AS, Norway). Blood samples were collected from normal (n = 90), clinically ill (n = 33), PTE (n = 40) and DIC (n = 37) diagnosed dogs. The each collected samples were tested with above mentioned two devices and compared to identify any differences. There were no statistically significant differences in D-dimer levels in between two devices either from normal or all diseased dogs. Moreover, the correlation co-efficient was r = + 0.9725. The calculated correlation was significant (p < 0.001) which proves its accuracy. Therefore, SelexOn™ canine D-dimer device is reliable and suitable device to use for the clinical test for measuring of blood D-dimer concentration in dogs.