An Association of Fragile X Associated Tremor/Ataxia Syndrome (FXTAS) with Three Common Neurological Problems: A Review
ShujaYaqub, Robert SooHoo, Devyn Cottor
Affiliation
Center for Mind and Brain, University of California, Davis, United States
Corresponding Author
Hassaan Tohid, Center for Mind and Brain, University of California, Davis, 95618, United States, E-mail: hassaantohid@hotmail.com
Citation
Tohid, H., et al. An Association of Fragile X Associated Tremor/Ataxia Syndrome (FXTAS) with Three Common Neurological Problems: A Review. (2016) Int J Neurol Brain Disord 3(3): 1- 5.
Copy rights
© 2016 Tohid, H. This is an Open access article distributed under the terms of Creative Commons Attribution 4.0 International License.
Keywords
Abstract
Aim: To study the association of Fragile X associated tremor/ataxia syndrome (FXTAS) with Alzheimer’s disease and Lewy Body Dementia.
Method: A systematic search was performed in various data bases and journals of Neurology. In total over 600 articles were reviewed and out of those, 39 were selected based on selection criteria.
Results: FXTAS is associated with Alzheimer’s disease and Lewy Body dementia because so many symptomatic and pathophysiological similarities are found between FXTAS and these two neurodegenerative diseases.
Conclusion: The association of FXTAS with neurodegenerative illnesses like Alzheimer’s disease and Lewy Body dementia is present because of many similarities between them. However, some dissimilarities do exist and some questions remain in addressing the pathophysiology of this association. Therefore we recommend more research in the near future to understand this association to develop and utilize wide-reaching therapies.