Affiliation

• ¹Department of Public Health Dentistry, JSS Dental College and Hospital, Jagadguru Sri Shivarathreeshwara University, Mysuru, India
• ²Department of Preventive and Public Health Dentistry, Fukuoka Dental College, Tamura, Sawara-ku, Fukuoka, Japan
• ³Department of General Dentistry, Fukuoka Dental College, Tamura, Sawara-ku, Fukuoka, Japan
• ⁴Tanabe Clinic for Preservative Dentistry, Mizutani, Higashi-ku, Fukuoka, Japan
• ⁵Department of Periodontics, JSS Dental College and Hospital, Jagadguru Sri Shivarathreeshwara University, Mysuru, India

Corresponding Author

Dr. Priyanka Sharma, JSS Dental College and Hospital, Jagadguru Sri Shivarathreeshwara University, SS Nagar, Mysuru – 570015, India; E-mail: priyankasharmamds@gmail.com>

Citation

Sharma, P., et al. Effectiveness of Probiotic Lactobacillus salivarius WB21 Tablets on Oral Malodor among Patients Attending Dental Institution in Mysuru City, India – An Open Label Pilot Trial. (2017) J Dent Oral Care 4(1): 1- 8.

Copy rights

Sharma, P. This is an Open access article distributed under the terms of Creative Commons Attribution 4.0 International License.

Keywords

Abstract

Aim: To evaluate the effectiveness of Lactobacillus salivarius WB21 tablets on oral malodor among adult patients attending a dental institution in Mysuru city, India.
Methods: This open label trial was conducted in September 2015 by a single calibrated principal investigator on 21 adult patients with genuine halitosis. With prior informed consent, participants were given 2.0 × 10⁹ L. salivarius WB21 and xylitol in tablet form to be consumed three times after food daily. Oral malodor and clinical parameters were evaluated at the baseline and after 2 and 4 weeks. Genuine halitosis was further classified to physiological and pathological halitosis.
Results: Bleeding on probing, tongue coating score and stimulated salivary flow were significantly improved at 2 weeks compared to baseline levels. A significant decrease in plaque index, average probing pocket depth and organoleptic score was observed at 4 weeks. The changes during 4 weeks in all clinical parameters were significantly greater in the participants with pathological halitosis compared to physiological halitosis.
Conclusions: Oral administration of probiotic Lactobacilli improved clinical and oral malodor parameters. Further large-scale randomized clinical trials are necessary to explain the effectiveness of probiotics in management of oral malodor and periodontal diseases.