Electrical Control of Cancer Invasion: A Mini Review
Kejun Zhang1, Ming Chen1, Yong He2, Jianxin Jiang3, Min Zhao4 and Li Li2*
Affiliation
- 1Department of Clinical Laboratory, Daping Hospital, Third Military Medical University, Chongqing 400042, China
- 2Department of Respiratory Disease, Daping Hospital, Third Military Medical University, Chongqing 400042, China
- 3State key laboratory of trauma, burns and combined injury, Daping Hospital, Third Military Medical University, Chongqing 400042, China
- 4Department of Dermatology, Institute for Regenerative Cures, University of California at Davis, CA 95817, USA
Corresponding Author
Li Li, Department of Respiratory Disease, Daping Hospital, Third Military Medical University, Chongqing 400042, China. Tel: 86-23-68757793; E-mail: lili10119@126.com
Citation
Li Li., et al. Electrical Control of Cancer Cell Migration: A Mini Review. (2015) Int J Cancer Oncol 2(1): 1-3.
Copy rights
© 2015 Li Li. This is an Open access article distributed under the terms of Creative Commons Attribution 4.0 International License.
Keywords
Abstract
Cancer metastasis, definded as the spread of cancer cells to distant organs, accounts for many cancer-related deaths. Migration is one of many factors implicated in this phenomenon. Mechanisms controling directional cancer invasion are not fully understood. Endogenous electric fields (EFs) have been demonstrated to be an important guidance cue controling directional cell migration. Indeed, many types of cancer cells migrate directionally in an EF. Understanding the electrical control of cancer invasion will help develop noval approaches to prevent cancer metastasis.
