Affiliation

• ¹Dermatology Department, Faculty of Medicine and Health Sciences, University Hospital, Sana’a University, Sana’a, Yemen
• ²Faculty of Dentistry, Sana’a University, Sana’a, Yemen

Corresponding Author

Dr. Mohammad Ali Alshami, Dermatology Department, University Hospital, Sana’a University, Sana’a, Yemen, P.O. Box 1950, E-mail: mohammadalshami62@gmail.com

Citation

Alshami A.M, et al. Epidermolytic Hyperkeratosis: A Case Report from Yemen. (2016) Invest Dermatol Venerol Res 2(1): 61-63.

Copy rights

© 2016 Alshami A.M. This is an Open access article distributed under the terms of Creative Commons Attribution 4.0 International License.

Keywords

Abstract

  Epidermolytic hyperkeratosis is a rare autosomal dominant disorder of cornification with a prevalence of 1:100,000 to 1:300,000, which affect both sexes equally. We report the case of a 10-year-old girl who presented to the dermatology clinic with dirty brown, corrugated hyperkeratotic plaques involving joint flexures and the trunk. She had similar lesions arranged in a cobblestone pattern over the knees, elbows, and dorsal hands and feet, in addition to multiple superficial erosions. She had a history of generalized erythroderma and trauma-related blistering at the time of birth. All other family members were healthy, and had no such skin manifestations.