First trimester fetal biparietal diameter and head circumference in Chinese population
Min CHEN1,2,3,4,5,6#*, Xin YANG7#, Qizhen ZHENG1,2,3,4, Chun Quan OU8,9, Chin Peng LEE6, Yung Hang LAM10, Mary Hoi Yin TANG6
Affiliation
- 1Department of Fetal Medicine and Prenatal Diagnosis, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510150, China
- 2Obstetrics & Gynecology Institute of Guangzhou, Guangzhou,510150, China
- 3The Medical Centre for Critical Pregnant Women in Guangzhou, Guangzhou, 510150, China
- 4Key Laboratory for Major Obstetric Diseases of Guangdong Province, Guangzhou, 510150, China
- 5Key Laboratory of Reproduction and Genetics of Guangdong Province
- 6Department of Obstetrics and Gynaecology, The University of Hong Kong, Queen Mary Hospital, Hong Kong, China
- 7Prenatal Diagnosis Center, Guangzhou Maternal and Neonatal Hospital, Guangzhou, 510623, China
- 8Department of Community Medicine, Faculty of Medicine, The University of Hong Kong, Hong Kong, China
- 9Department of Biostatistics, Southern Medical University, Guangzhou, China
- 10Hong Kong Prenatal Diagnosis Center, Hong Kong, China
- ##The two authors contribute equally to this work
Corresponding Author
Min CHEN, Department of Fetal Medicine and Prenatal Diagnosis, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510150, China, E-mail: edchen99@gmail.com
Citation
Min, C., et al. First Trimester Fetal Biparietal Diameter And Head Circumference In Chinese Population. (2017) J Gynecol Neonatal Biol 3(1): 27-31.
Copy rights
© 2017 Min, C. This is an Open access article distributed under the terms of Creative Commons Attribution 4.0 International License.
Keywords
Abstract
Objectives:To establish the reference ranges for fetal biparietal diameter and head circumference obtained by transabdominal ultrasound examination in the first trimester in Chinese women.
Methods:In this prospective cross-sectional study, 1351 normal singleton fetuses were examined transabdominally by 2 experienced observers in the first trimester of pregnancy in which the CRL was between 55 and 84 mm. Measurements of Biparietal Diameter (BPD), head circumference (HC) were prospectively collected. Charts and predictive equations were constructed from data obtained.
Results:Measurements of BPD, HC were correlated with CRL. CRL-based predictive equations were calculated using polynomial least squares regression analysis. HC = 7.710583 + 1.387393 * CRL-0.0037807 * CRL², R² = 0.5735, P = 0.000. BPD = 6.855277 + 0.2389065 * CRL, R² = 0.5355, P = 0.000. CRL-specific biometric charts were constructed.
Conclusions:There was a general increase in fetal biparietal diameter and head circumference with CRL. Chinese fetal biometry might be of help in first-trimester ultrasound examination in the local population.
