Affiliation

Department of Medical Oncology, National Institute of Oncology, Rabat, Morocco

Corresponding Author

Asmaa Lakhdissi, Department of Medical Oncology, National Institute of Oncology, Rabat, Morocco, E-mail: asmaalakhdissi@gmail.com

Citation

Lakhdissi, A,. et. al. Primarysplenic Large Cell B Lymphoma: Case Report. (2016) J Gastro Dis Liver Func 2(2): 73- 76.

Copy rights

© 2016 Lakhdissi, A. This is an Open access article distributed under the terms of Creative Commons Attribution 4.0 International License.

Keywords

Abstract

Background: Primary splenic lymphoma is a rare disease with heterogeneous definition, compromising less than 1% of non-Hodgkin’s lymphoma.
Case presentation: We are reporting a case of 50 year old man who presented splenomegaly, fever, weight loss and night sweats. The investigations revealed a splenomegaly with splenic lesion which cancorrespond to abscess. The patient underwent splenectomy for definitive diagnosis and treatment. Diagnosis of primary diffuse large B cell lymphoma of the spleen was made and confirmed by immunochemistry and the patient received 6 cycles of RCHOP (Rituximab + cyclophosphamide + Adriamycin + vincristine + prednisone) and he is currently well and in complete remission more than 1 year after diagnosis.
Conclusion: Primary splenic lymphoma is rare; splenectomy is an important step in its diagnosis and treatment. Early splenectomy combined with chemotherapy is an optimal strategy.