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Publish Date : 2015-10-15
Journal of Gastrointestinal Disorders and Liver function

Relation between Patients with Gastric Helicobacter pylori Infection and Dyslipidemia

Edson Guzmán-Calderón1,3,5,6*
Pedro Montes2,3,6 Eduardo Monge2,3,4
Article information 

Affiliation

  • 1Gastroenterology Unit of Hospital Nacional Edgardo Rebagliati Martins, Lima, Peru
  • 2Gastroenterology Unit of Hospital Daniel Alcides Carrion, Callao, Peru
  • 3Universidad Peruana de Ciencias Aplicadas (UPC)
  • 4Universidad Peruana Cayetano Heredia (UPCH)
  • 5Universidad San Martin de Porres (USMP)
  • 6Clinica Internacional Lima Peru

Corresponding Author

Gerly Edson Guzmán Calderon, Prol Manco II, 115- Condominio Villa Marina, Block- A, 1101–San Miguel, Lima, Perú. Tel: +5115665465/ +51984767112; E-mail: edson_guzman@hotmail.com

Citation

Guzman, G.E., et al. Relation between Patients with Gastric Helicobacter Pylori Infection and Dyslipidemia. (2015) J Gastrointest Disord Liver Func 1(1): 11- 14.

Copy rights

© 2015 Guzman, G.E. This is an Open access article distributed under the terms of Creative Commons Attribution 4.0 International License.

Keywords

Abstract

 

Objective: To evaluate the relation between gastric H. pylori infection and dyslipidemia.
Methods: Eligible subjects were all adult; we enrolled those patients with dyspepsia who had undergone esophagogastroduodenoscopy. They were divided in 2 groups: Case group: patients who have a histologic diagnosis of infection for H. pylori. Control group: Patients who had previous negative biopsy for H. pylori. All patients had basic serology and lipid profiles, both groups were compared.
Results: 120 patients were evaluate, 63 were female (52.5%). Of 77 patients with dyslipidemia, 40 were positive H. pylori (51.9%), and 20 of 43 non – dyslipidemic patients were positive H. pylori (46.5%). Cholesterol values were 196.6 ± 42.1 and 191.7 ± 29.5; triglyceride 164.4 ± 89.1 and 139.2 ± 69.1; LDL 119.2 ± 33.8 and 115.9 ± 27.4; VLDL 33.1 ± 17.6 and 29.1 ± 15.6, HDL: 44.4 ± 9.1 and 42.5 ± 10.7 for the positive and negative H. pylori groups, respectively. “p” values in all cases were not statistically significant: cholesterol (p = 0.4), triglycerides (p = 0.08), HDL (p = 0.3), LDL (p = 0.5), VLDL (p = 0.1).
Conclusions: Gastric H. pylori infection does not have significant relation with the presence of dyslipidemia. The alterations of the serum lipids profiles (cholesterol, triglycerides, LDL and VLDL) are discreetly higher in the patients infected by H. pylori, but they are not statistically significant.