The Influence of Targeting Central Venous Pressure (CVP) on Early Graft Function after Living Donor Kidney Transplantation
Gavrilovska A1, Srceva-Jovanovski M1, Temelkovska M1, Stavridis S2, Spasovski G3
Affiliation
- 1University Clinic of Traumatology, Orthopedia, Anesthesia, Intensive Care and Emergency Center, Macedonia
- 2University Clinic of Urology, Macedonia
- 3University Clinic of Nephrology, Macedonia
Corresponding Author
Maja Mojsova Mijovska, M.D, Ph.D, University Clinic of Traumatology, Orthopedia, Anesthesia, Reanimation, Intensive Care and Emergency Center Skopje, R. Macedonia, E-mail: majamojsova777@gmail.com
Citation
Mijovska M.M., et al. The Influence of Targeting Central Venous Pressure (CVP) on Early Graft Function after Living Donor Kidney Transplantation. (2017) J Anesth Surg 4(1): 32- 35.
Copy rights
© 2017 Mijovska M.M. This is an Open access article distributed under the terms of Creative Commons Attribution 4.0 International License.
Keywords
Abstract
Introduction: Early graft function is very important and can be achieved with an adequate intraopeartive perfusion characteristics of the graft and urine output. The goal of this study was to examine the influence of targeting CVP on early graft function.
Material and methods: After approval of Ethical committee of the Medical Faculty-Skopje we obtained inform consent of 60 patients ASA 2 - 3 undergoing renal transplantation of living-related person in the Clinic of Urology-Skopje. A prospective clinical study which was performed in the period of 2 years. They were divided in 2 groups of thirty patients: group A receiving normal saline intraoperativly targeting for CVP 15 mmHg until vascular clamps were off and group B receiving normal saline 10 ml/kg/h. We recorded onset of diuresis and total urine output from unclamping the renal vessels to the end of the surgery in both groups and postoperative serum, urine creatinin and FENa % in 3 times (3,12,36 hours).
Results: The onset of diuresis in seconds was insignificantly longer in group B p > 0.05 (p = 0.31) we didn’t find any statistical differences in postoperative serum creatinin in both groups.
Conclusion: Our study didn’t show any benefit from targeting CVP to 15 mmHg. We couldn’t find any significant differences on onset of diuresis and urine output after the unclamping the vessels.
