Upper Extremity Function after Transradial Percutaneous Coronary Intervention Short-Term Interim Results of the ARCUS Study
Alexander JJ Ijsselmuiden1*, Carlo. A.J Holtzer2*, Eva M Zwaan3, Robert-Jan M van Geuns4, Niels van Royen5, Esther Moerman6, Giovanni Amoroso7, Marco J.PF. Ritt8, Ton A Schreuders9, Marcel J.M Kofflard3
Affiliation
- 1Department of Cardiology, Amphia Hospital, Breda, the Netherlands
- 2Department of Plastic, Reconstructive, and Hand Surgery, Albert Schweitzer Hospital, Dordrecht, the Netherlands
- 3Department of Cardiology, Albert Schweitzer Hospital, Dordrecht, the Netherlands
- 4Department of Cardiology, Erasmus Medical Centre, Rotterdam, the Netherlands
- 5Department of Cardiology, VU University Medical Centre, Amsterdam, the Netherlands
- 6Department of Plastic, Reconstructive, and Hand Surgery, Onze Lieve Vrouwe Gasthuis, Amsterdam, the Netherlands
- 7Department of Cardiology, Onze Lieve Vrouwe Gasthuis, Amsterdam, the Netherlands
- 8Department of Plastic, Reconstructive, and Hand Surgery, VU University Medical Centre, Amsterdam, the Netherlands
- 9Hand and Pols centre, Dordrecht, the Netherlands
- #Authors contributed equally
Corresponding Author
IJsselmuiden, A.J.J., MD, PhD, Department of Cardiology, Amphia Hospital, Mailbox 901584800 RK Breda, The Netherlands, Tel: 0031-0765954090; Fax: 0031-076-5953340; E-mail: sijsselmuiden@amphia.nl
Citation
IJsselmuiden, A.J.J., et al. Upper Extremity Function after Transradial Percutaneous Coronary Intervention: Short-Term Interim Results of the ARCUS Study. (2017) J Heart Cardiol 3(2): 34-39.
Copy rights
© 2017 IJsselmuiden, A.J.J. This is an Open access article distributed under the terms of Creative Commons Attribution 4.0 International License.
Keywords
Abstract
Aims: To examine the short-term effects of transradial percutaneous coronary interventions on the upper extremities function.
Method and results: This is an interim analysis of the Effects of trAnsRadial per- CUtaneouS coronary intervention on upper extremity function (ARCUS) study. Out of 191 patients evaluated at 2 weeks after they had undergone a transradial percutaneous coronary intervention, 120 (62.8 % ) had manifestations of upper extremity dysfunction on the side of the intervention. The main abnormalities were a decrease in sensibility, a ≥ 15 % increase in the Disabilities of the Hand and Shoulder questionnaire score and a ≥ 2 cm increase in hand and forearm volumes. Radial artery occlusions occurred in 12 patients in the upper extremity dysfunction versus 1 patient in the no upper extremity dysfunction group (p = 0.03). Patients with upper extremity dysfunction were significantly more likely to have a family history of heart disease (50 % vs. 26.8 % ; p = 0.002). In addition, there was a trend (p = 0.07) toward a greater proportion of previous smokers in the group with upper extremity dysfunction than in the other group.
Conclusions: Upper extremity dysfunction after transradial percutaneous coronary intervention is a medical concern. However, our original score may be overly sensitive and overestimate the rate of upper extremity dysfunction. Further analyses are needed, as well as perhaps a modification of the primary endpoint.
