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Publish Date : 2016-12-02
Journal of Bioinformatics, Proteomics and Imaging Analysis

In Vivo Imaging of Lung Tumor Growth Using In-Line X-Ray Phase Contrast Technique

Rongbiao Tang
Rongbiao Tang1*, Fuhua Yan1, Guo-Yuan Yang2, Ke-Min Chen1*
Article information 

Affiliation

  • 1Department of Radiology, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China
  • 2Neuroscience and Neuroengineering Center, Med-X Research Institute, Shanghai Jiao Tong University, Shanghai 200030, China

Corresponding Author

Rongbiao Tang, Department of Radiology, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China, E-mail: tangme8688258@sina.com &
Department of Radiology, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China, E-mail: keminchenrj@163.com

Citation

Tang, R., et al. In vivo imaging of lung tumor growth using in-line x-ray phase contrast technique. (2016) J Imaging Sci 3(1): 174-176.

Copy rights

© 2016 Tang, R. This is an Open access article distributed under the terms of Creative Commons Attribution 4.0 International License.

Keywords

Abstract

  The primary purpose of present study was to investigate the application value of Synchrotron Radiation Phase Contrast Imaging (SR-PCI) for the evaluation of lung tumor growth. Comparison between Absorption Contrast Imaging (ACI) and inline PCI was observed in living tumor-bearing mice. Early lung cancer was shown at pre-injection, 12 h and 36 h post-injection in the same mouse. PCI was performed to noninvasively monitor tumor progression in a longitudinal study. It was concluded that PCI was a helpful imaging modality for detecting early lung tumor and monitoring tumor growth in mouse models.