Elimination of the Heavy Metals Toxicity and Diseases in Disruption of Extracellular Matrix (ECM) Proteins and Cell Adhesion Intelligent Nanomolecules Adjustment in Cancer Metastases Using Metalloenzymes and under Synchrotron Radiation
Affiliation
Faculty of Chemistry, California South University, 14731 Comet St. Irvine, CA 92604, USA
Corresponding Author
Alireza Heidari, Faculty of Chemistry, California South University, 14731 Comet St. Irvine, CA 92604, USA, E-mail: Scholar.Researcher.Scientist@gmail.com
Citation
Heidari, A. Elimination of the Heavy Metals Toxicity and Diseases in Disruption of Extracellular Matrix (ECM) Proteins and Cell Adhesion Intelligent Nanomolecules Adjustment in Cancer Metastases Using Metalloenzymes and under Synchrotron Radiation. (2017) Lett Health Biol Sci 2(2): 78- 81.
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© 2017 Heidari, A. This is an Open access article distributed under the terms of Creative Commons Attribution 4.0 International License..
Keywords
Heavy Metals Toxicity; Cancer Metastases; Extracellular Matrix
Introduction
Heavy metals Nano compounds are important synthetic intermediates in organic, medicinal and pharmaceutical chemistry and are valuable in the preparation of biologically and pharmaceutically relevant Nano materials[1-11]. The oxidation of heavy metals Nano compounds is the most straight forward method for the synthesis of heavy metals Nano compounds[12-24]. However, only a few reports are available where a given oxidant is suitable for controlled synthesis of heavy metals Nano compounds[25-27]. It is often noticed that heavy metals Nano compounds oxidation is accompanied by several disadvantages such as long reaction times, inconvenient reaction conditions, expensive oxidants, undesired side and now yields[28-32]. An important goal in this area of research has been to develop catalyst systems for mild and selective oxidations of heavy metals Nano compounds. Metalloenzymes capable of activating dioxygen in order to oxidize exogenous substrates play an important and inspirational role in the design of new oxidation catalysts. Particularly, heavy metals Nano compounds oxygenases have become attractive targets for extensive research efforts toward the synthesis of nanomolecule analogues of their active sites.
Modern science is based on interaction among disciplines. Pharmaceutical and medicinal chemistry has transformed the materials of everyday life, but this is merely a quick look of the future of pharmaceutical and medicinal materials such as intelligent nanomolecules that behave as a sensor, self–reproducing pharmaceutical and medicinal Nano compounds, intelligent nanomolecules that work (Nano–Engineering) and even intelligent nanomolecules that think may transform our world in ways not yet imagined (Figures 1 and Figure 2)[33-35]. These developments are the result of cooperation among pharmaceutical chemists, physicists, engineers, material scientists, computer experts, pharmacists, medicinal chemists and many others. The most dramatic developments at the beginning of the twenty–first century are new methods in chemistry, pharmacology, pharmaceutical sciences and medicine from collaborations among pharmaceutical and medicinal chemists and biologists. In this short communication, a transcendental approach to biofield changing premix metal powders characteristics as metalloenzymes for elimination of the heavy metals toxicity and diseases in disruption of Extracellular Matrix (ECM) proteins and cell adhesion intelligent nanomolecules adjustment in cancer metastases induced by osteosarcoma, chondrosarcoma, carcinoid, carcinoma, Ewing’s sarcoma, fibrosarcoma and secondary hematopoietic solid or soft tissue tumors under synchrotron radiation have been investigated.
Figure 1: Schematic of elimination of the heavy metals toxicity and diseases in disruption of Extracellular Matrix (ECM) proteins and cell adhesion intelligent nanomolecules adjustment in cancer metastases[33-55].
Figure 2: A Scanning Electron Microscope (SEM) image of interaction between heavy metals toxicity and diseases in disruption of Extracellular Matrix (ECM) proteins and cell adhesion intelligent nanomolecules adjustment in cancer metastases using metalloenzymes and under synchrotron radiation[33-55].
On the other hand, it is well-known that biofield changing premix metal powders characteristics as metalloenzymes for elimination of the heavy metals toxicity and diseases is critical role and effect in most of reactions. This role is important, when you do these reactions in disruption of Extracellular Matrix (ECM) proteins and cell adhesion intelligent nanomolecules adjustment in cancer metastases induced by osteosarcoma, chondrosarcoma, carcinoid, carcinoma, Ewing’s sarcoma, fibrosarcoma and secondary hematopoietic solid or soft tissue tumors under synchrotron radiation. For example, in pharmaceutical and medicinal manufactures, biofield changing premix metal powders characteristics as metalloenzymes has prominent role in purity, yield, stability and expense for elimination of the heavy metals toxicity and diseases. Furthermore, biofield changing premix metal powders characteristics as metalloenzymes is depending on low hazard and easily recovering. Biofield changing premix metal powders characteristics as metalloenzymes for elimination of the heavy metals toxicity and diseases is one of the valuable and sensitive disruption of Extracellular Matrix (ECM) proteins and cell adhesion intelligent nanomolecules adjustment in cancer metastases induced by osteosarcoma, chondrosarcoma, carcinoid, carcinoma, Ewing’s sarcoma, fibrosarcoma and secondary hematopoietic solid or soft tissue tumors under synchrotron radiation. There are many literatures about disruption of Extracellular Matrix (ECM) proteins and cell adhesion intelligent nanomolecules adjustment in cancer metastases induced by osteosarcoma, chondrosarcoma, carcinoid, carcinoma, Ewing’s sarcoma, fibrosarcoma and secondary hematopoietic solid or soft tissue tumors, but most of them use hard reaction conditions. For this purpose, we have investigated the process of disruption of Extracellular Matrix (ECM) proteins and cell adhesion intelligent nanomolecules adjustment in cancer metastases induced by osteosarcoma, chondrosarcoma, carcinoid, carcinoma, Ewing’s sarcoma, fibrosarcoma and secondary hematopoietic solid or soft tissue tumors under synchrotron radiation in various solvents such as Dichloromethane (DCM or Methylene Chloride), Acetone, Tetrahydrofuran (THF) and Ethyl Acetate and also have reported purity, yield and expense of produce, stability and crystallinity of them. By this optimization, we are able to disrupt Extracellular Matrix (ECM) proteins and cell adhesion intelligent nanomolecules adjustment in cancer metastases induced by osteosarcoma, chondrosarcoma, carcinoid, carcinoma, Ewing’s sarcoma, fibrosarcoma and secondary hematopoietic solid or soft tissue tumors and have a crystalline form with more stability and therapeutically effect under synchrotron radiation.
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